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Cymbalta Side Effects
Cymbalta (generic name - duloxetine) is a relatively new medication.
It was approved by the FDA in August 2004 as a treatment for major depression
in adults, and in September 2004 for the management of diabetic peripheral
neuropathic pain, a symptom of nerve damage that affects up to 5 million Americans.
Serious Cymbalta Side Effects
The following are considered to be possible serious Cymbalta side effects
- an allergic reaction (difficulty breathing; closing of the throat; swelling
of the lips, tongue, or face; or hives);an irregular heartbeat or pulse; low
blood pressure (dizziness, weakness); high blood pressure (severe headache,
blurred vision); chills or fever; unusual bleeding or bruising; a rash or
hives. If the patient experiences any of these, they should stop taking Cymbalta
immediately and contact a doctor.
Less Serious Cymbalta Side Effects
The following are considered to be possible less serious Cymbalta side effects
- headache, tremor, nervousness, or anxiety; difficulty concentrating; constipation;
nausea, diarrhea, dry mouth, or changes in appetite or weight; weakness; increased
sweating; sleepiness or insomnia; or decreased sex drive, impotence, or difficulty
having an orgasm. Patients that experience any of these side effects can continue
taking Cymbalta but be sure to let a doctor know.
It is quite possible for side effects other than those listed here to occur.
If this happens and/or if any seem particularly strange or bothersome, contact
a healthcare provider.
Special Cymbalta Precautions
Exercise caution when driving, operating machinery, or performing other hazardous
activities as Cymbalta may cause dizziness or drowsiness. If you experience
either, avoid these activities totally.
While taking Cymbalta, the patient may need to be monitored for signs of worsening
symptoms of depression. This, especially important for Cymbalta patients who
are 18 years of age or younger. The doctor may need to monitor for the following
symptoms: anxiety, panic attacks, difficulty sleeping, irritability, hostility,
impulsivity, severe restlessness, and mania (mental and/ or physical hyperactivity).
These symptoms may be associated with the development of worsening symptoms
of depression.
Before taking Cymbalta, the patient should let the doctor know if they - have
liver disease; have kidney disease; narrow angle glaucoma; have diabetes;
drink alcohol regularly; have high blood pressure; suffer from seizures; or
suffer from mania or have suicidal thoughts. If any are true, the doctor may
either adjust to a special dosage or not recommend Cymbalta at all.
Cymbalta is in the FDA pregnancy category C. This means that babies exposed
to Cymbalta and/ or other drugs of the same class during the third trimester
of pregnancy may develop medical complications. Thus, it is advised that you
not take this medication without first talking to your doctor if you are pregnant
or could become pregnant during treatment. Cymbalta is also known to pass
into breast milk and may affect a nursing infant.
Do not take Cymbalta if you have taken a monoamine oxidase inhibitor (MAOI)
such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate)
during the last two weeks. You should wait at least five days after you stop
taking Cymbalta before taking a MAOI. Additionally, do not take Cymbalta if
you are taking thioridazine (Mellaril).
If Cymbalta is taken with certain other prescription and non-prescription
drugs, the effects of either could be increased, decreased, or altered. It
is especially important to check with your doctor before combining Lipitor
with any of the following drugs - an antiarrhythmic such as flecainide (Tambocor)
or propafenone (Rythmol), (and others); a tricyclic antidepressant such as
amitriptyline (Elavil), imipramine (Tofranil), doxepin (Sinequan), nortriptyline
(Pamelor), (and others); venlafaxine (Effexor); a phenothiazine such as chlorpromazine
(Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine
(Trilafon), prochlorperazine (Compazine), (and others); a quinolone antibiotic
such as trovafloxacin (Trovan), ciprofloxacin (Cipro), ofloxacin (Floxin),
(and others); quinidine; or; a selective serotonin reuptake inhibitor (SSRI)
such as fluoxetine (Prozac, Sarafem), paroxetine (Paxil, Pexeva), fluvoxamine
(Luvox), and others.
Warning: This information is intended to
supplement, not be a substitute for the expertise and judgment of
a doctor. Please consult a doctor for final and more detailed information
about the possible side effects of this prescription medication.
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